Endometriosis can be challenging to diagnose based on clinical presentation alone
This disease has a wide range of symptoms and significant symptom overlap with other gynecologic and non-gynecologic conditions1
Consider endometriosis early in your differential diagnosis1-19
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Select one of the conditions below to see the possible symptom overlap with endometriosis |
Select condition:
Dysmenorrhea
Non-menstrual pelvic pain
Dyspareunia
Heavy or irregular bleeding
Dysuria
Dyschezia
Constipation
Diarrhea
Lower abdominal or back pain
ENDOMETRIOSIS
SYMPTOMS
Dysuria
Dyschezia
Diarrhea
Dysmenorrhea
Non-menstrual pelvic pain
Dyspareunia
Heavy or irregular bleeding
Constipation
Lower abdominal or back pain
Anemia
Urinary frequency or urgency
ENDOMETRIOSIS
SYMPTOMS
SHARED
SYMPTOMS
UTERINE
FIBROIDS
SYMPTOMS
Dyschezia
Constipation
Diarrhea
Dysmenorrhea
Non-menstrual pelvic pain
Dyspareunia
Heavy or irregular bleeding
Dysuria
Lower abdominal or back pain
Fever
Vaginal discharge
ENDOMETRIOSIS
SYMPTOMS
SHARED
SYMPTOMS
PELVIC
INFLAMMATORY
DISEASE
SYMPTOMS
Dysuria
Dyschezia
Constipation
Diarrhea
Lower abdominal or back pain
Dysmenorrhea
Non-menstrual pelvic pain
Dyspareunia
Heavy or irregular bleeding
Anemia
ENDOMETRIOSIS
SYMPTOMS
SHARED
SYMPTOMS
ADENOMYOSIS
SYMPTOMS
Constipation
Diarrhea
Lower abdominal or back pain
Dysmenorrhea
Non-menstrual pelvic pain
Dyspareunia
Heavy or irregular bleeding
Dysuria
Dyschezia
Urinary frequency or urgency
Fever
ENDOMETRIOSIS
SYMPTOMS
SHARED
SYMPTOMS
OVARIAN
CYSTS
SYMPTOMS
Dysmenorrhea
Dysuria
Heavy or irregular bleeding
Non-menstrual pelvic pain
Dyspareunia
Dyschezia
Constipation
Diarrhea
Lower abdominal/back pain
ENDOMETRIOSIS
SYMPTOMS
SHARED
SYMPTOMS
IRRITABLE
BOWEL
SYNDROME
SYMPTOMS
Heavy or irregular bleeding
Dysuria
Dyschezia
Constipation
Dysmenorrhea
Non-menstrual pelvic pain
Dyspareunia
Diarrhea
Lower abdominal or back pain
Fever
Anemia
ENDOMETRIOSIS
SYMPTOMS
SHARED
SYMPTOMS
INFLAMMATORY
BOWEL
DISEASE
SYMPTOMS
Dysmenorrhea
Heavy or irregular bleeding
Dyschezia
Constipation
Diarrhea
Non-menstrual pelvic pain
Dyspareunia
Dysuria
Lower abdominal or back pain
Urinary frequency or urgency
ENDOMETRIOSIS
SYMPTOMS
SHARED
SYMPTOMS
INTERSTITIAL
CYSTITIS
SYMPTOMS
This symptoms list is not all-inclusive.
References:
1. Mao AJ, Anastasi JK. Diagnosis and management of endometriosis: the role of the advanced practice nurse in primary care. J Am Acad Nurse Pract. 2010;22(2):109-116. 2. American College of Obstetricians and Gynecologists. Practice bulletin no. 114: management of endometriosis. Obstet Gynecol. 2010;116(1):223-236. 3. Sturpe DA, Pincus KJ. Endometriosis. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach, 9th ed. New York, NY: McGraw-Hill; 2014. 4. Association of Professors of Gynecology and Obstetrics. Diagnosis & Management of Endometriosis: Pathophysiology to Practice. Educational Series on Women's Health Issues. https://pdfs.semanticscholar.org/2f57/078beb656b74691969f0a494021dca8e094f.pdf. Accessed June 10, 2019. 5. Woo J, Armstrong AY. Gynecologic disorders. In: Papadakis MA, McPhee SJ, Rabow MW, eds. Current Medical Diagnosis & Treatment 2017. New York, NY: McGraw-Hill; 2017. 6. Uterine fibroids. Mayo Clinic website. http://www.mayoclinic.org/diseases-conditions/uterine-fibroids/symptoms-causes/syc-20354288. Accessed June 10, 2019. 7. The Practice Committee of the American Society for Reproductive Medicine. Treatment of pelvic pain associated with endometriosis: a committee opinion [published correction appears in Fertil Steril. 2015;104(2):498]. Fertil Steril. 2014;101(4):927-935. 8. Goje O. Pelvic inflammatory disease (PID). Merck Manual website. http://www.merckmanuals.com/professional/gynecology-and-obstetrics/vaginitis,-cervicitis,-and-pelvic-inflammatory-disease-pid/pelvic-inflammatory-disease-pid. Updated May 2018. Accessed August 22, 2018. 9. Kilpatrick CC. Uterine adenomyosis. Merck Manual website. https://www.merckmanuals.com/professional/gynecology-and-obstetrics/miscellaneous-gynecologic-disorders/uterine-adenomyosis. Updated May 2019. Accessed June 10, 2019. 10. Evans P. Vaginal bleeding. In: South-Paul JE, Matheny SC, Lewis EL, eds. Current Diagnosis & Treatment: Family Medicine, 4th ed. New York, NY: McGraw-Hill; 2015. 11. Adenomyosis. Mayo Clinic website. https://www.mayoclinic.org/diseases-conditions/adenomyosis/symptoms-causes/syc-20369138. Updated June 8, 2018. Accessed June 10, 2019. 12. Heniff M, Fleming HRB. Abdominal and pelvic pain in the nonpregnant female. In: Tintinalli JE, Stapczynski JS, Ma OJ, Yealy DM, Meckler GD, Cline DM, eds. Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 8th ed. New York, NY: McGraw-Hill; 2016. 13. Ovarian cysts. Mount Sinai website. http://www.mountsinai.org/health-library/diseases-conditions/ovarian-cysts. Accessed October 19, 2017. 14. Benign ovarian cysts. Johns Hopkins Medicine website. http://www.hopkinsmedicine.org/gynecology_obstetrics/specialty_areas/gynecological_services/conditions/ovarian_cysts.html. Accessed June 10, 2019. 15. Owyang C. Irritable bowel syndrome. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine, 19th ed. New York, NY: McGraw-Hill; 2014. 16. Moleski SM. Irritable bowel syndrome (IBS). Merck Manual website. http://www.merckmanuals.com/professional/gastrointestinal-disorders/irritable-bowel-syndrome-ibs/irritable-bowel-syndrome-ibs. Updated November 18, 2017. Accessed June 10, 2019. 17. Inflammatory bowel disease (IBD). Mayo Clinic website. https://www.mayoclinic.org/diseases-conditions/inflammatory-bowel-disease/symptoms-causes/syc-20353315. Updated April 2019. Accessed June 10, 2019. 18. Interstitial cystitis. Mayo Clinic website. https://www.mayoclinic.org/diseases-conditions/interstitial-cystitis/symptoms-causes/syc-20354357. Updated May 14, 2019. Accessed June 10, 2019. 19. Warren JW. Dysuria, bladder pain, and the interstitial cystitis/bladder pain syndrome. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine, 19th ed. New York, NY: McGraw-Hill; 2014.